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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BROX
All Species:
30
Human Site:
T294
Identified Species:
60
UniProt:
Q5VW32
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW32
NP_653296.2
411
46476
T294
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
V
Chimpanzee
Pan troglodytes
XP_001173118
411
46488
T294
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
V
Rhesus Macaque
Macaca mulatta
XP_001099998
411
46403
T294
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
V
Dog
Lupus familis
XP_536151
461
51635
T344
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Q7
411
46183
T294
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
A
Rat
Rattus norvegicus
Q4V8K5
411
46173
T294
L
C
K
E
Y
G
E
T
K
G
P
G
P
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512145
469
53140
T352
L
C
K
E
Y
G
E
T
K
G
P
G
T
T
A
Chicken
Gallus gallus
XP_419397
411
46534
T294
L
C
K
E
Y
G
E
T
K
G
P
G
T
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KQV2
411
46106
M294
L
C
K
E
Y
R
Q
M
K
G
P
G
S
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120754
420
47151
I303
L
C
E
E
Y
G
K
I
N
G
P
A
P
R
V
Nematode Worm
Caenorhab. elegans
Q22885
427
48281
A304
M
A
A
M
Y
A
T
A
T
G
P
G
T
R
I
Sea Urchin
Strong. purpuratus
XP_784283
330
36694
F220
A
F
E
T
G
K
Q
F
K
M
A
D
N
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.2
84.8
N.A.
91.7
92.4
N.A.
78.4
86.3
N.A.
74.2
N.A.
N.A.
45
39.5
34.7
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96.8
96.8
N.A.
82.7
92.9
N.A.
86.3
N.A.
N.A.
60
60.8
50.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
66.6
N.A.
N.A.
60
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
73.3
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
9
0
9
0
0
9
9
0
0
42
% A
% Cys:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
17
84
0
0
67
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
75
0
0
0
92
0
84
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% I
% Lys:
0
0
75
0
0
9
9
0
84
0
0
0
0
0
0
% K
% Leu:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
9
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
92
0
59
0
0
% P
% Gln:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% S
% Thr:
0
0
0
9
0
0
9
67
9
0
0
0
25
75
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
92
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _